GAMUT D-78-S
BONE NEOPLASMS CLASSIFIED BY TUMOR MATRIX OR TISSUE OF ORIGIN 


          CHONDROID (Cartilage-Forming) TUMORS
BENIGN
1. Chondroblastoma (Codman tumor)
2. Chondromyxoid fibroma 
3. Enchondroma    , incl. enchondromatosis (Ollier disease; Maffucci S.)
4. Osteochondroma , incl. hereditary multiple exostoses (multiple cartilaginous exostoses; osteochondromatosis)
5. Periosteal (juxtacortical) chondroma


MALIGNANT
1. Chondrosarcoma   (multiple types) (See D-81-S3)


          OSTEOID (Bone-Forming) TUMORS
BENIGN
1. Bone island (enostosis) (incl. osteopoikilosis and osteopathia striata)
2. Ossifying fibroma  (face, jaws)
3. Osteoblastoma
4. Osteofibrous dysplasia (esp. tibia)
5. Osteoid osteoma
6. Osteoma


MALIGNANT
1. Osteosarcoma     (multiple types) (See D-81-S2)


          FIBROUS CONNECTIVE TISSUE TUMORS
BENIGN
1. Cortical/periosteal desmoid (cortical avulsive injury)
2. Desmoplastic fibroma
3. Fibromatosis (esp. multicentric infantile myofibromatosis)
4. Fibromyxoma
5. Nonossifying fibroma (fibroxanthoma)
6. Periosteal (juxtacortical) fibroma


MALIGNANT
1. Fibrosarcoma
2. Malignant fibrous histiocytoma 


          TUMORS OF FATTY TISSUE ORIGIN
BENIGN
1. Lipoma , intraosseous or parosteal
2. Liposclerosing myxofibrous tumor (LSMFT)


MALIGNANT
1. Liposarcoma


          TUMORS OF VASCULAR ORIGIN
BENIGN
1. Angiomatosis (hemangiomatosis; lymphangiomatous)
2. Glomus tumor
3. Hemangioma
4. Hemangioendothelioma (benign)
5. Hemangiopericytoma (benign)
6. Lymphangioma
7. Massive osteolysis (Gorham vanishing bone disease)


MALIGNANT
1. Angiosarcoma
2. Hemangioendothelioma (malignant) 
3. Hemangiopericytoma (malignant)
4. Kaposi sarcoma


          TUMORS OF NEURAL ORIGIN (RARE IN BONE)
BENIGN
1. Neurilemoma (schwannoma)
2. Neurofibroma (incl. neurofibromatosis)


MALIGNANT
1. Malignant peripheral nerve sheath tumor (MPNST) (neurofibrosarcoma)


          GIANT CELL-CONTAINING TUMORS
BENIGN
1. Aneurysmal bone cyst
2. Bone cyst (complicated by fracture)
3. Brown tumor of hyperparathyroidism
4. Chondroblastoma (Codman tumor)
5. Chondromyxoid fibroma
6. Fibrous dysplasia
7. Giant cell granuloma 
8. Giant cell tumor (benign)
9. Osteoblastoma
10. Osteofibrous dysplasia (esp. tibia)


MALIGNANT
1. Giant cell tumor (malignant)
2. Malignant fibrous histiocytoma
3. Osteosarcoma





References